GPAT 2012 Model Question Paper
Pattern of Question Paper
The GPAT-2012 question paper will consist of one hundred fifty (150 Nos.) multiple choice objective questions only. Candidates have to mark the correct choice by darkening the appropriate bubble against each question on an Optical Response Sheet (ORS). Each right answer will carry three marks while for each wrong answer, 1/3 (one third) marks will be deducted. ‘No attempt’ will fetch zero mark.
Each question will have four choices for the answer. Out of these, only one choice is correct/most appropriate. Each choice contains stand-alone statement(s)/phrase(s)/ data/structure(s).
The type of questions asked in this examination would be to evaluate a candidate’s aptitude and knowledge of Pharmacy subjects and applied subjects (as per the syllabus given in the website) taught at B. Pharmacy level, which may involve basic principles, facts, formulae/laws, understanding of the fundamental ideas, and application or drawing observations of the fundamentals of pharmacy discipline. Some examples of the multiple choice objective questions are given below:
Q.1 All of the given four drugs cause vasodilatation. Choose the correct statement about them? [P) Bradykinin [Q] Minoxidil [R] Acetylcholine [S] Hydralazine
(A) P & Q cause release of nitric oxide
(B) Q & R do not cause release of nitric oxide
(C) R & S cause release of nitric oxide
(D) P & S do not cause release of nitric oxide
Q.2 Study the following two statements and choose the correct answer: [P] Antibodies are serum proteins providing immunity. [Q] IgG provides immunity to new born babies while IgM is the first generated antibody.
(A) P is correct and Q is incorrect (B) P is incorrect and Q is correct
(C) Both P and Q are correct (D) Both P and Q are incorrect
Q.3 Determine the correctness or otherwise of the following Assertion [a] and the Reason [r]: Assertion[a]: For a pharmaceutical powder true density is greater than the granule density. Reason [r]: Mercury displacement used for determining granule density, allows penetration of liquid into internal pores of the particles.
(A) [a] is true but [r] is false
(B) Both [a] and [r] are false
(C) Both [a] and [r] are true and [r] is the correct reason for [a]
(D) Both [a] and [r] are true but [r] is NOT the correct reason for [a]
Q.4 A glycoalkaloid [P] contains sulphur in addition to nitrogen in its molecule. [Q] is glycosidic in nature. [R] can be hydrolysed to an alkaloid. [S] always contains endocyclic nitrogen in its molecule. Choose the correct option?
(A) P&R (B) Q&S
(C) Q&R (D) P&Q
Q.5 Five-membered heteroaromatic compounds show a much higher rate of electrophilic aromatic substitution reactions than the six-membered ones. This is due to which one of the following reasons?
(A) Five-membered heteroaromatic compounds have higher circulating electron density in the ring than the six-membered ones
(B) Five-membered heteroaromatic compounds have lower circulating electron density in the ring than the six-membered ones
(C) Five-membered rings are smaller in size than the six membered ones which affects their reaction rates
(D) Six membered heteroaromatic rings are flat while the five-membered ones are puckered
Q.6 Followings are the desirable properties of the liquid phase used in GLC EXCEPT for one of the followings. Identify that?
(A) It should be inert to the analytes
(B) It should have high viscosity at operating temperature
(C) It should have low vapour pressure at the operating temperature
(D) It should have a high resolving power
Q.7 In an optically active organic compound a chiral carbon has the following attached groups:
[P]
[Q] 
[R] 
[S] 
Using ‘Sequence Rules’ choose the correct order of priority of the groups?
(A) Q>P>S>R (B) P>Q>R>S
(C) Q>P>R>S (D) P>Q>S>R
Q.8 The following statements are given: [P] Conformational isomers are interconvertible by rotation around a single bond while configurational isomers can not be interconverted without breaking a bond. [Q] Configurational isomers could be optically active or optically inactive while conformational isomers are optically inactive [R] Geometric isomers must have a double bond in their structures [S] Geometric and optical isomers are the two distinct categories of configurational isomers. Choose the correct combination of statements?
(A) P, Q & S are true while R is false (B) P,R & S are true while Q is false
(C) Q, R & S are true while P is false (D) P, Q & R are true while S is false
Q.9 Choose the correct statement for writing the sequence of amino acids in a polypeptide?
(A) Amino terminal is to be written on the left hand side while the carboxyl terminal is to be written on the right hand side
(B) Carboxyl terminal is to be written on the left hand side while the amino terminal is to be written on the right hand side
(C) Any of the amino acid terminals can be written on any sides but it is to be mentioned by Specifying the amino terminal and the carboxyl terminal in abbreviations
(D) It varies from author to author how the sequence of amino acids in a polypeptide is to be written
Q.10 Given are the four statements about NMR: [P] 13CMR is a less sensitive technique than PMR [Q] Both 13C and 1H have I=1/2 [R] Precessional frequency of the nucleus is directly proportional to the applied magnetic field [S] Deuterium exchange studies can be performed to ascertain protons attached to heteroatoms. Choose the correct combination of statements?
(A) P, Q & R are true while S is false (B) R, S & Q are true while P is false
(C) S, P & Q are true while R is false (D) All are true
* Negative Marking: There is a one-third (1/3) negative marking for each wrong answer
Source: www.gpat.in
Pattern of Question Paper
The GPAT-2012 question paper will consist of one hundred fifty (150 Nos.) multiple choice objective questions only. Candidates have to mark the correct choice by darkening the appropriate bubble against each question on an Optical Response Sheet (ORS). Each right answer will carry three marks while for each wrong answer, 1/3 (one third) marks will be deducted. ‘No attempt’ will fetch zero mark.
Each question will have four choices for the answer. Out of these, only one choice is correct/most appropriate. Each choice contains stand-alone statement(s)/phrase(s)/ data/structure(s).
The type of questions asked in this examination would be to evaluate a candidate’s aptitude and knowledge of Pharmacy subjects and applied subjects (as per the syllabus given in the website) taught at B. Pharmacy level, which may involve basic principles, facts, formulae/laws, understanding of the fundamental ideas, and application or drawing observations of the fundamentals of pharmacy discipline. Some examples of the multiple choice objective questions are given below:
Q.1 All of the given four drugs cause vasodilatation. Choose the correct statement about them? [P) Bradykinin [Q] Minoxidil [R] Acetylcholine [S] Hydralazine
(A) P & Q cause release of nitric oxide
(B) Q & R do not cause release of nitric oxide
(C) R & S cause release of nitric oxide
(D) P & S do not cause release of nitric oxide
Q.2 Study the following two statements and choose the correct answer: [P] Antibodies are serum proteins providing immunity. [Q] IgG provides immunity to new born babies while IgM is the first generated antibody.
(A) P is correct and Q is incorrect (B) P is incorrect and Q is correct
(C) Both P and Q are correct (D) Both P and Q are incorrect
Q.3 Determine the correctness or otherwise of the following Assertion [a] and the Reason [r]: Assertion[a]: For a pharmaceutical powder true density is greater than the granule density. Reason [r]: Mercury displacement used for determining granule density, allows penetration of liquid into internal pores of the particles.
(A) [a] is true but [r] is false
(B) Both [a] and [r] are false
(C) Both [a] and [r] are true and [r] is the correct reason for [a]
(D) Both [a] and [r] are true but [r] is NOT the correct reason for [a]
Q.4 A glycoalkaloid [P] contains sulphur in addition to nitrogen in its molecule. [Q] is glycosidic in nature. [R] can be hydrolysed to an alkaloid. [S] always contains endocyclic nitrogen in its molecule. Choose the correct option?
(A) P&R (B) Q&S
(C) Q&R (D) P&Q
Q.5 Five-membered heteroaromatic compounds show a much higher rate of electrophilic aromatic substitution reactions than the six-membered ones. This is due to which one of the following reasons?
(A) Five-membered heteroaromatic compounds have higher circulating electron density in the ring than the six-membered ones
(B) Five-membered heteroaromatic compounds have lower circulating electron density in the ring than the six-membered ones
(C) Five-membered rings are smaller in size than the six membered ones which affects their reaction rates
(D) Six membered heteroaromatic rings are flat while the five-membered ones are puckered
Q.6 Followings are the desirable properties of the liquid phase used in GLC EXCEPT for one of the followings. Identify that?
(A) It should be inert to the analytes
(B) It should have high viscosity at operating temperature
(C) It should have low vapour pressure at the operating temperature
(D) It should have a high resolving power
Q.7 In an optically active organic compound a chiral carbon has the following attached groups:
[P]
[Q] [R] [S] Using ‘Sequence Rules’ choose the correct order of priority of the groups?
(A) Q>P>S>R (B) P>Q>R>S
(C) Q>P>R>S (D) P>Q>S>R
Q.8 The following statements are given: [P] Conformational isomers are interconvertible by rotation around a single bond while configurational isomers can not be interconverted without breaking a bond. [Q] Configurational isomers could be optically active or optically inactive while conformational isomers are optically inactive [R] Geometric isomers must have a double bond in their structures [S] Geometric and optical isomers are the two distinct categories of configurational isomers. Choose the correct combination of statements?
(A) P, Q & S are true while R is false (B) P,R & S are true while Q is false
(C) Q, R & S are true while P is false (D) P, Q & R are true while S is false
Q.9 Choose the correct statement for writing the sequence of amino acids in a polypeptide?
(A) Amino terminal is to be written on the left hand side while the carboxyl terminal is to be written on the right hand side
(B) Carboxyl terminal is to be written on the left hand side while the amino terminal is to be written on the right hand side
(C) Any of the amino acid terminals can be written on any sides but it is to be mentioned by Specifying the amino terminal and the carboxyl terminal in abbreviations
(D) It varies from author to author how the sequence of amino acids in a polypeptide is to be written
Q.10 Given are the four statements about NMR: [P] 13CMR is a less sensitive technique than PMR [Q] Both 13C and 1H have I=1/2 [R] Precessional frequency of the nucleus is directly proportional to the applied magnetic field [S] Deuterium exchange studies can be performed to ascertain protons attached to heteroatoms. Choose the correct combination of statements?
(A) P, Q & R are true while S is false (B) R, S & Q are true while P is false
(C) S, P & Q are true while R is false (D) All are true
* Negative Marking: There is a one-third (1/3) negative marking for each wrong answer
Source: www.gpat.in
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GPAT